Q: If a healthcare worker did not have a titer drawn after the HBV vaccine was completed, how long afterward could we assume that he/she is a responder/non-responder? Many titers wane after years and are no longer detectable. How do we know the worker continues to be protected?
A: If the healthcare worker did not have a titer, you must assume non-responder status. Regarding testing, and boosters, booster doses of the hepatitis B vaccine are not necessary, and periodic testing to monitor antibody concentrations after completion of the vaccine series is not recommended. Any blood or body fluid exposure sustained by an unvaccinated, susceptible person should lead to the initiation of the hepatitis B vaccine series.